Automating NGS-Based HLA Typing for Stem Cell Transplantations

Case Study  Anthony Nolan, United Kingdom
Case Study Anthony Nolan
More about NGS-based HLA Typing

What's in the Case Study?

 In this Case Study, the Histocompatibility and Immunogenetics Team at Anthony Nolan describes the implementation of an automated Next-Generation Sequencing (NGS)-based Human Leukocyte Antigen (HLA) typing method, leveraging the flexibility of GenDx’s NGSGo kits and Hamilton’s automated liquid handling systems, and the power of Illumina’s sequencing and analysis technologies.

Highlights of this Case Study:

  • Anthony Nolan’s role in HLA typing and Stem cell transplantations
  • Benefits of NGS-based HLA typing in comparison with other sequencing-based methods
  • Flexibility and adaptability of Hamilton Liquid Handlers in the implementation of genomic workflows



 
NGS-based HLA Typing Workflow

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Hamilton Company specializes in the development, manufacturing and customization of precision measurement devices, automated liquid handling workstations, and sample management systems.

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Hamilton Robotics provides solutions for fully automated workflows. Our automated liquid handler workstations provide consistent results for assays, ranging from low-throughput pipetting protocols to high-throughput systems with integrated sample storage.
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